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Multi-Feed Enzyme: Case Study of a Successful Integrator

Learn from a case study of an integrator that successfully applied Biosolution's multi-functional feed enzyme (cellulase, protease, amylase). At a dosage of 0.5–1 kg/ton feed, feed efficiency increased by 5–10%, feed costs dropped drastically without sacrificing livestock performance.

M. Faisal Hidayat S.Pt., M.Sc. December 21, 2025 9 min read
Multi-Feed Enzyme: Case Study of a Successful Integrator

Multi-Feed Enzyme: Case Study of a Successful Integrator Applying a Multi-Functional Formula

In the competitive feed industry, efficiency is key. One innovation now widely adopted by feed mills and integrators is the use of multi-feed enzymes that can break down various feed components simultaneously. Multi-functional feed enzymes combining cellulase, protease, and amylase offer a comprehensive solution to improve feed digestibility, reduce costs, and enable the use of alternative feed ingredients. This article presents a case study of an integrator that successfully applied Biosolution's multi-functional enzyme formula and reaped tangible results.

Why Multi-Functional Feed Enzymes Are a Game Changer

Conventional feed often contains crude fiber, complex proteins, and starch that are difficult to digest. Without exogenous enzymes, these nutrients are wasted and can cause digestive issues. Multi-feed enzymes provide a solution with three main activities:

  • Cellulase: Breaks down cellulose into easily absorbed glucose, enabling the use of high-fiber feed ingredients such as rice bran, cassava pulp, or straw.
  • Protease: Breaks down complex proteins into peptides and amino acids, improving protein digestibility and reducing nitrogen excretion.
  • Amylase: Hydrolyzes starch into simple sugars, providing quick energy for livestock.

Biosolution's Multi-Functional Feed Enzyme Formula contains Aspergillus oryzae which naturally produces all three enzymes, plus lipase to aid fat digestion. At a dosage of only 0.5–1 kg per ton of feed, this enzyme works synergistically to increase feed efficiency by 5–10%.

Case Study: Medium-Scale Poultry Integrator

PT. Maju Farm, a poultry integrator in East Java with a population of 500,000 broilers per cycle, faced challenges from rising corn and soybean meal prices. They decided to test multi-feed enzymes on 100,000 broilers over 35 days. The control feed used a standard formula, while the treatment feed replaced 10% of corn with rice bran and 5% of soybean meal with palm kernel meal, plus 0.75 kg/ton of Multi-Functional Feed Enzyme Formula.

Results Achieved

After 35 days, the nutrition team recorded the following data:

Parameter Control Treatment Change
Final body weight (g) 2,100 2,085 -0.7% (not significant)
FCR 1.55 1.48 -4.5%
Feed cost per kg weight IDR 14,200 IDR 12,900 -9.2%
Mortality 3.2% 3.0% -6.3%

Although final body weight was slightly lower (not statistically significant), FCR improved significantly and feed cost dropped nearly 10%. This success prompted PT. Maju Farm to adopt the multi-functional enzyme for its entire population.

Synergistic Mechanism of Cellulase, Protease, and Amylase

The advantage of multi-feed enzymes lies in the synergistic action of the three enzymes. Here is the scientific explanation:

Cellulase: Unlocking Trapped Nutrients

Cellulase breaks down plant cell walls composed of cellulose and hemicellulose. In fibrous feed ingredients, nutrients like protein and starch are often trapped within the fiber matrix. By degrading fiber, cellulase releases these nutrients so other enzymes can work more effectively. Research from FAO shows that cellulase can increase the metabolizable energy of poultry feed by up to 5%.

Protease: Optimizing Protein Utilization

Protease from Aspergillus oryzae has optimal activity at pH 4-6, suitable for the poultry digestive tract. This enzyme breaks down protein into peptides and amino acids ready for absorption. Thus, essential amino acid requirements can be met even when using low-protein raw materials such as palm kernel meal.

Amylase: Quick Energy Source

Amylase hydrolyzes starch into maltose and glucose. In broilers, quick energy is essential for growth. With amylase, starch from grains or tubers can be digested more completely, reducing the risk of sticky digesta and improving slaughter weight.

Implementation in Feed Mills: Tips and Best Practices

For feed mills looking to adopt multi-feed enzymes, here are recommended steps:

  1. Small-scale trial: Conduct a trial on 5-10% of the population to evaluate livestock response.
  2. Adjust formulation: Reduce the use of expensive raw materials (corn, soybean meal) and replace them with fibrous or low-protein alternatives, then add the enzyme at the recommended dosage.
  3. Ensure uniform mixing: The enzyme should be added during feed mixing, ideally through a premix or spray. A dosage of 0.5–1 kg per ton of feed is sufficient for optimal results.
  4. Monitor parameters: Observe FCR, body weight, mortality, and feed cost. Compare with the control.
  5. Evaluate and scale up: If results are positive, apply to the entire population.

Biosolution also provides consulting services to help feed mills with formulation and enzyme optimization.

Advantages of Biosolution's Multi-Functional Feed Enzyme Formula

The Multi-Functional Feed Enzyme Formula product has several advantages over single enzymes:

  • Multi-activity in one product: Contains cellulase, protease, amylase, and lipase from a single optimized strain of Aspergillus oryzae.
  • Heat stable: Special production process makes the enzyme resistant to pelleting temperatures up to 80°C.
  • Safe for all species: Tested on broilers, layers, pigs, and fish.
  • Low dosage: Only 0.5–1 kg per ton of feed, making it economical.

Conclusion

The case study of PT. Maju Farm proves that the application of multi-feed enzymes with a formula of cellulase, protease, and amylase can reduce feed costs by up to 9% without sacrificing livestock performance. Biosolution's multi-functional feed enzyme is the right solution for feed mills and integrators looking to improve efficiency and competitiveness. With low dosage and proven results, this innovation deserves to be part of modern livestock nutrition strategies.

Interested in applying this technology? Consult your feed needs with Biosolution's expert team via WhatsApp. See the full product or read related articles about the benefits of enzymes for feed efficiency.

#multi-feed enzyme#multi-functional enzyme#cellulase#protease#amylase#feed efficiency#feed mill#Biosolution

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